Open Thread: Who Is Your Favorite On-Screen Pairing?

Lately I’ve found myself thinking about great screen duos. Be it Dean and Jerry, Han and Chewie or Lucy and Desi, certain pairings on television and the silver screen are nothing less than magical. To kick off this week,  we want you to tell us about who your favorite on-screen pairing is. But more than that, we want you to try to tell us about the essence of why you think your chosen two has resonated through the lives of everyone who watched and enjoyed their collaboration and felt that chemistry that only a truly special duo can create, like weaving thread into entertainment gold.